Quinolines and derivatives

Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.36% | 500 MG

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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It acts as a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker. It induces apoptosis and can be utilized for malaria research. It has demonstrated cytotoxicity against MES-SA cells.

• Antiarrhythmic agent
• Potent, orally active, selective cytochrome P450db inhibitor
• K+ channel blocker
• Induces apoptosis
• Can be used for malaria research

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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.4% | 25 G

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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It is a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker. It can induce apoptosis and is used for malaria research.

• Antiarrhythmic agent
• Potent, orally active, selective cytochrome P450db inhibitor
• K+ channel blocker with an IC50 of 19.9 μM
• Induces apoptosis
• Can be used for malaria research
• Shows cytotoxicity against MES-SA cells
• Shows effects on the PTZ-induced seizure threshold in vivo

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Medchemexpress LLC Cinchonine ((8R,9S)-cinchonine) | 118-10-5 | MFCD00064372 | 99.7% | 294.39 | C19H22N2O | 500g

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Cinchonine is a natural compound present in Cinchona bark with antimalarial antitumor anti-inflammatory anti platelet-aggregation and anti-obesity properties Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3 Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]

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Medchemexpress LLC Mefloquine | 53230-10-7 | 99.96% | 378.31 | 200 MG

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Mefloquine is an orally active and potent quinoline antimalarial agent that also functions as an anti-SARS-CoV-2 entry inhibitor. It is a K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM. It can be utilized for research related to malaria, systemic lupus erythematosus, and cancer, selectively inhibiting prostate cancer (PCa) cell growth with an IC50 of ~10 μM by inducing hyperpolarization of mitochondrial membrane potential and ROS generation.

• Orally active and potent quinoline antimalarial agent
• Functions as an anti-SARS-CoV-2 entry inhibitor
• K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM
• Can be used for malaria, systemic lupus erythematosus, and cancer research
• Selectively inhibits prostate cancer cell growth

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Medchemexpress LLC Mefloquine (Standard) | 53230-10-7 | 378.31 | 1 G

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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent, and also functions as an anti-SARS-CoV-2 entry inhibitor. Mefloquine is a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. It can be utilized for malaria, systemic lupus erythematosus, and cancer research.

• Analytical standard grade
• Reference standard supplied assay
• Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
• Suitable for various research and analytical applications
• Potential for malaria, systemic lupus erythematosus, and cancer research

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Chem-Impex International, Inc. Gatifloxacin | 112811-59-3 | MFCD00895399 | 1G

Gatifloxacin, 112811-59-3, MFCD00895399, 1G

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Medchemexpress LLC 7-bromoquinoline-4-carboxylic acid | 31009-04-8 | MFCD11108751 | 96.1% | 252.06 | C10H6BrNO2 | 1 G

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7-Bromoquinoline-4-carboxylic acid is a brominated quinoline carboxylic acid used as an intermediate in organic synthesis and medicinal chemistry research. It is supplied as a gray to brown solid (C10H6BrNO2; MW 252.06; CAS 31009-04-8) with typical HPLC purity of 96.12%. Storage recommendations: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).

• Used as an intermediate for organic synthesis
• Suitable for medicinal chemistry research applications
• Supplied as a stable solid with defined storage conditions
• Provided with HPLC purity data for quality assessment
• Batch certificate of analysis available for traceability

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Ambeed 4Aminoisophthalic acid

4-Aminoisophthalic acid, 33890-03-8, 98%

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eMolecules​ EMOLECULES INC

5000474097 4-BROMOPYRIMIDIN-2-AMINE 10G

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